bw必威西汉姆联官网, bw必威西汉姆联官网, 副教授
教育经历：
(1) 2014-09 至2019-06, 武汉大学, 高分子化学与物理, 博士(导师：张先正)
(2) 2010-09 至2014-06, 湖北大学, 化员工物学, 学士
科研与学术工作经历：
（1）2019-06 至2020-12, 美国康奈尔大学, 博后
（2）2021-07 至今, bw必威西汉姆联官网, bw必威西汉姆联官网, 讲师
（3）2024-02 至2024-06, 香港理工大学, 生物医学工程学院, 香江学者
近五年主持或参加的科研项目/课题：
(1) 国家自然科学基金委员会, 青年科学基金项目, 52203170, 双重响应型工程化植物囊泡内外协同“加热”增强肿瘤免疫治疗, 2023-01 至 2025-12, 30万元, 结题, 主持
(2) 江苏省科学技术厅, 青年基金项目, BK20220384, 工程化植物囊泡的构建及其“冷”肿瘤智能化免疫调控的研究, 2022-07 至 2025-06, 20万元, 结题, 主持
(3) 全国博士后管委会办公室和香港学者协会, 博后项目, XJ2023048, 香江学者计划-力学因素对肿瘤转移的影响, 2024-02 至 2026-02, 72万元, 结题, 主持
(4) bw必威西汉姆联官网引进人才科研启动基金项目，NY221131，中草药囊泡复合体的抗肿瘤免疫治疗研究, 2021-07 至 2024-07，10万元, 结题, 主持。
(5) 江苏省”双创博士”项目，工程化植物囊泡双重调控重塑“冷”肿瘤， JSSCBS20220641, 2022-10至2024-10，15万元, 结题, 主持。
(6) 有机电子与信息显示国家重点实验室，主任基金项目，光刺激响应的工程化植物囊泡重塑 “冷”肿瘤，GZ222087, 2023-07至2025-07，5万元, 结题, 主持。
代表性研究成果和学术奖励况：
(1) Wan Shuang-Shuang; Wang Ke-Peng; Huang Pei-Hong; Guo Xian; Liu Wu-Rui; Li Yao-Cheng; Zhang Jing-Jing; Li Zhi-Yang; Song Jia-Cheng; Yang Wen-Jing; Zhang Xian-Zheng; Ding Xian-Guang; Leong David- Tai; Wang Lian-Hui; Mechanoelectronic Stimulation of Autologous Extracellular Vesicle Biosynthesis Implant for Gut Microbiota Modulation, Nature Communications, 2024, 15(1):3343. IF: 16.6.
(2) Wan Shuang-Shuang*; Liu Wu-Rui; Wu Qian; Wang Ke-Peng; Li Yao-Cheng; Huang Pei-Hong; Wu Yu; Mu Yun-Fei; Fan Yu-Lin; Tao Jun; Yao Jia; Peng Fei; Zou Yu; Wang Lian-Hui; Yuan Zhi-Yao;* and Ding Xian-Guang; Nanobiohybrid Extracellular Vesicle Nanoreactor with Improving Metabolical Activity for Biocatalytic Therapy. ACS NANO, 2024, 8(47):32899-32909.
(3) Zhang Jing-Jing*; Wan Shuang-Shuang*; Zhou Hao*; Du Jia-Xin; Li Yao-Cheng; Zhu Hou-Juan; Weng Li-Xing; Ding Xian-Guang; Wang Lian-Hui; Programmed Nanocloak of Commensal Bacteria-Derived Nanovesicles Amplify Strong Immunoreactivity against Tumor Growth and Metastatic Progression, ACS NANO, 2024, 18(13): 9613-9626.
(4) Tao Jun; Ning Weiqing; Shi Xuzhi; Wu Tingting; Liu Shenzhe; Wan Shuangshuang*; Wang Shouju; Chen Jia*; Wang Lianhui*. Self-delivery nanomedicine for selective mitochondrial copper depletion and oxidative stress amplification. ACS Nano, 2025, 19 (37): 33587-33600.
(5) Tao Jun; Zhou;* Li Haozhen; Rui Jing; Qi Qinghui; Jin Hengyu; Shuangshaung Wan* and Wang Lianhui*. Light-driven jet-propelled nanomotors for enhanced drug penetration and therapy. Journal of Materials Chemistry B, 2026.
(6) Wan, Shuang-Shuang*; Cheng, Qian*; Zeng, Jin-Yue; Zhang, Xian-Zheng; A Mn(III)-Sealed MOF Nanoreactor for Redox-Unlocked Tumor Theranostics, ACS Nano, 2019, 13(16): 6561-6571. IF: 17.1.
(7) Wan, Shuang-Shuang*; Zhang, Lu*; Zhang, Xian-Zheng; An ATP-Regulated Ion Transport Nanosystem for Homeostatic Perturbation Therapy and Sensitizing Photodynamic Therapy by Autophagy Inhibi tion of Tumors, ACS Central Science, 2019, 5(2): 327-340.
(8) Wan, Shuang-Shuang; Zeng, Jin-Yue; Cheng, Han; Zhang, Xian-Zheng; ROS-Induced NO Generat ion for Gas Therapy and Sensitizing Photodynamic Therapy of Tumor, Biomaterials, 2018, 185: 51-62. IF:14.0.
(9) Zhang, Lu*; Wan, Shuang-Shuang*; Li, Chu-Xin; Xu, Lu; Cheng, Han; Zhang, Xian-Zheng; An Ad enosine Triphosphate-Responsive Autocatalytic Fenton Nanoparticle for Tumor Ablation with Self-Su pplied H2O2 and Acceleration of Fe(III)/Fe(II) Conversion, Nano Letters, 2018, 18(12): 7609-7618. IF: 10.8.
(10) Wan, Shuang-Shuang; Liu, Miao‐Deng; Cheng, Qian; Cheng, Han; Zhang, Xian‐Zheng; A Mitochondria‐Driven Metabolic Sensing Nanosystem for Oxygen Availability and Energy Blockade of Cancer, Advanced Therapeutics, 2020, 3(6): 2000019.
(11) Wan, Shuang-Shuang*; Tao Jun*; Wu, Qian; Liu Wu Rui; Ding, Xian‐Guang; Zhang, Xian- Zheng; Size-Controllable Nanosystem with Double Responsive for Deep Photodynamic Therapy, Pharmaceutics, 2023, 15(3): 940.